{"id":34316,"date":"2023-12-12T10:03:59","date_gmt":"2023-12-12T01:03:59","guid":{"rendered":"https:\/\/www.mti.co.jp\/?p=34316"},"modified":"2023-12-12T10:03:59","modified_gmt":"2023-12-12T01:03:59","slug":"%e4%b8%8d%e5%a6%8a%e6%b2%bb%e7%99%82%e3%81%ab%e9%96%a2%e3%81%99%e3%82%8b%e5%85%b1%e5%90%8c%e7%a0%94%e7%a9%b6%e7%ac%ac%e4%ba%8c%e5%bc%be%e3%81%a8%e3%81%97%e3%81%a6%e4%b8%8d%e5%a6%8a%e6%b2%bb%e7%99%82-8","status":"publish","type":"post","link":"https:\/\/www.mti.co.jp\/?p=34316","title":{"rendered":"\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306b1\u65e5\u7a0b\u5ea6\u306e\u4e00\u6642\u7684\u306a\u6708\u7d4c\u5468\u671f\u306e\u9045\u308c"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-full wp-image-24872\" src=\"https:\/\/www.mti.co.jp\/wp-content\/uploads\/2020\/01\/c55ccc4339046d448ccbb6d93aa2702a.png\" alt=\"\" width=\"313\" height=\"142\" srcset=\"https:\/\/www.mti.co.jp\/wp-content\/uploads\/2020\/01\/c55ccc4339046d448ccbb6d93aa2702a.png 313w, https:\/\/www.mti.co.jp\/wp-content\/uploads\/2020\/01\/c55ccc4339046d448ccbb6d93aa2702a-150x68.png 150w, https:\/\/www.mti.co.jp\/wp-content\/uploads\/2020\/01\/c55ccc4339046d448ccbb6d93aa2702a-300x136.png 300w\" sizes=\"auto, (max-width: 313px) 100vw, 313px\" \/><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>\u56fd\u7acb\u6210\u80b2\u533b\u7642\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\uff08\u6771\u4eac\u90fd\u4e16\u7530\u8c37\u533a\u3001\u7406\u4e8b\u9577\uff1a\u4e94\u5341\u5d50\u9686\uff09\u793e\u4f1a\u533b\u5b66\u7814\u7a76\u90e8\u306e\u68ee\u5d0e\u83dc\u7a42\u3001\u518d\u751f\u533b\u7642\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u306e\u7d30\u8c37\u8061\u53f2\u3001\u6885\u6fa4\u660e\u5f18\u3001\u682a\u5f0f\u4f1a\u793e\u30a8\u30e0\u30c6\u30a3\u30fc\u30a2\u30a4\uff08\u6771\u4eac\u90fd\u65b0\u5bbf\u533a\u3001\u4ee3\u8868\u53d6\u7de0\u5f79\u793e\u9577\uff1a\u524d\u591a\u4fca\u5b8f\u3001\u4ee5\u4e0b\u300c\u30a8\u30e0\u30c6\u30a3\u30fc\u30a2\u30a4\u300d\uff09\u3089\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u5973\u6027\u306e\u5065\u5eb7\u60c5\u5831\u30b5\u30fc\u30d3\u30b9\u300e\u30eb\u30ca\u30eb\u30ca\u300f\u3092\u7528\u3044\u3066\u3001mRNA\u306e\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306e\u6708\u7d4c\u5468\u671f\u306e\u9045\u308c\u306b\u3064\u3044\u3066\u7814\u7a76\u3092\u884c\u3044\u307e\u3057\u305f\u3002<br \/>\n\u305d\u306e\u7d50\u679c\u3001mRNA\u306e\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u521d\u56de\u63a5\u7a2e\uff081\u56de\u76ee\u30012\u56de\u76ee\u63a5\u7a2e\u306e\u3053\u3068\uff09\u30683\u56de\u76ee\u63a5\u7a2e\u76f4\u5f8c\u306e\u6708\u7d4c\u306b\u304a\u3044\u3066\u3001\u5e73\u5747\u3057\u3066\u7d041\u65e5\u7a0b\u5ea6\u306e\u5468\u671f\u306e\u9045\u308c\u304c\u898b\u3089\u308c\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u521d\u56de\u63a5\u7a2e\u3067\u898b\u3089\u308c\u305f\u6708\u7d4c\u5468\u671f\u306e\u9045\u308c\u306f\u4e00\u6642\u7684\u3067\u3042\u308a\u3001\u63a5\u7a2e\u5f8c2\uff5e4\u56de\u76ee\u306e\u6708\u7d4c\u3067\u307b\u307c\u901a\u5e38\u306e\u5468\u671f\u307e\u3067\u623b\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002\u305f\u3060\u521d\u56de\u63a5\u7a2e\u5f8c\u306b\u6bd4\u30793\u56de\u76ee\u63a5\u7a2e\u5f8c2\u301c4\u56de\u76ee\u306e\u6708\u7d4c\u3067\u306f\u5e73\u5747\u3057\u30660.2\u301c0.4\u65e5\u7a0b\u5ea6\u306e\u3054\u304f\u308f\u305a\u304b\u306a\u5468\u671f\u306e\u9045\u308c\u304c\u7d9a\u3044\u3066\u3044\u307e\u3057\u305f\u3002<br \/>\n\u672c\u7814\u7a76\u6210\u679c\u306b\u3088\u308a\u3001mRNA\u306e\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306b\u4e00\u6642\u7684\u304b\u3064\u3001\u308f\u305a\u304b\u306a\u6708\u7d4c\u5468\u671f\u306e\u9045\u308c\u304c\u751f\u3058\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002\u305f\u3060\u30573\u56de\u76ee\u4ee5\u964d\u306e\u8ffd\u52a0\u63a5\u7a2e\u306e\u6708\u7d4c\u5468\u671f\u3078\u306e\u5f71\u97ff\u306b\u3064\u3044\u3066\u306f\u8af8\u5916\u56fd\u3067\u306e\u5831\u544a\u6570\u3082\u5c11\u306a\u304f\u3001\u4eca\u5f8c\u306e\u3055\u3089\u306a\u308b\u7814\u7a76\u304c\u5fc5\u8981\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u3044\u305a\u308c\u306b\u305b\u3088\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u306e\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u306e\u30e1\u30ea\u30c3\u30c8\u306f\u5e83\u304f\u77e5\u3089\u308c\u3066\u3044\u308b\u3053\u3068\u304b\u3089\u3082\u3001\u6708\u7d4c\u5468\u671f\u3078\u306e\u5f71\u97ff\u3092\u5fc3\u914d\u3057\u3066\u63a5\u7a2e\u3092\u63a7\u3048\u308b\u5fc5\u8981\u306f\u306a\u3044\u3068\u8003\u3048\u3066\u304a\u308a\u307e\u3059\u3002\u672c\u7814\u7a76\u6210\u679c\u306f\u3001\u56fd\u969b\u7684\u306a\u5b66\u8853\u8a8c\u300cObstetrics &amp; Gynecology\u300d\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\uff08\u65e5\u672c\u6642\u95932023\u5e7412\u67088\u65e5\u306b\u516c\u958b\uff09\u3002<\/p>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 100%;\">\n<p><span style=\"font-size: 10pt; color: #ff0000;\">\u3010\u6ce8\u610f\u3011\u6708\u7d4c\u5468\u671f\u306f\u3001\u30b9\u30c8\u30ec\u30b9\u3084\u74b0\u5883\u306e\u5909\u5316\u306a\u3069\u69d8\u3005\u306a\u8981\u56e0\u3067\u4e71\u308c\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u672c\u7814\u7a76\u306f\u3001mRNA\u306e\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306e\u6708\u7d4c\u5468\u671f\u306e\u9045\u308c\u3068\u306e\u75ab\u5b66\u7684\u306a\u95a2\u9023\u3092\u660e\u3089\u304b\u306b\u3057\u305f\u3082\u306e\u3067\u3042\u308a\u3001mRNA\u30ef\u30af\u30c1\u30f3\u305d\u306e\u3082\u306e\u306e\u751f\u6b96\u6a5f\u80fd\u3078\u306e\u5f71\u97ff\u3092\u793a\u3057\u305f\u7814\u7a76\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span style=\"font-size: 10pt;\"><a href=\"https:\/\/www.mti.co.jp\/wp-content\/uploads\/2023\/12\/0161352a3d2ab457dfa6640c52a8eb52.png\" rel=\"lightbox[34316]\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter  wp-image-34321\" src=\"https:\/\/www.mti.co.jp\/wp-content\/uploads\/2023\/12\/0161352a3d2ab457dfa6640c52a8eb52.png\" alt=\"\" width=\"666\" height=\"410\" srcset=\"https:\/\/www.mti.co.jp\/wp-content\/uploads\/2023\/12\/0161352a3d2ab457dfa6640c52a8eb52.png 1767w, https:\/\/www.mti.co.jp\/wp-content\/uploads\/2023\/12\/0161352a3d2ab457dfa6640c52a8eb52-768x472.png 768w, https:\/\/www.mti.co.jp\/wp-content\/uploads\/2023\/12\/0161352a3d2ab457dfa6640c52a8eb52-1536x945.png 1536w\" sizes=\"auto, (max-width: 666px) 100vw, 666px\" \/><\/a>\u203b1\uff1a1\u56de\u76ee\u63a5\u7a2e\u524d\u306e\u30012\uff5e3\u56de\u306e\u6708\u7d4c\u5468\u671f\u306e\u5e73\u5747\u5024\u3002<\/span><br \/>\n<span style=\"font-size: 10pt;\">\u203b2\uff1a\u6a19\u6e96\u504f\u5dee\u3068\u306f\u3001\u5e73\u5747\u306b\u5bfe\u3059\u308b\u30c7\u30fc\u30bf\u306e\u6563\u3089\u3070\u308a\u306e\u5927\u304d\u3055\u3092\u8868\u3059\u6307\u6a19\u3067\u3001\u5927\u304d\u3044\u307b\u3069\u3001\u30c7\u30fc\u30bf\u304c\u6563\u3089\u3070\u3063\u3066\u3044\u308b\u3053\u3068\u3092\u8868\u3057\u307e\u3059\u3002\u4f8b\u3048\u3070\u88681\u306e\u521d\u56de\u63a5\u7a2e\u524d\u306e\u6708\u7d4c\u5468\u671f\u306e\u300c31.09\u00b15.69\u300d\u306f\u591a\u304f\u306e\u4eba\u306e\u6708\u7d4c\u5468\u671f\u306f\u7d0425.4\u65e5\u304b\u308936.8\u65e5\u306e\u9593\u3067\u3042\u308b\u3068\u3044\u3046\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/span><br \/>\n<span style=\"font-size: 10pt;\">\u203b3\uff1a95%\u4fe1\u983c\u533a\u9593\u3068\u306f\u540c\u3058\u7814\u7a76\u3092\u7e70\u308a\u8fd4\u3057\u305f\u6642\u306e\u7d50\u679c\u306e\u7bc4\u56f2\u306e\u3046\u3061\u300195%\u306e\u78ba\u7387\u3067\u7814\u7a76\u7d50\u679c\u304c\u53ce\u307e\u308b\u7bc4\u56f2\u306e\u3053\u3068\u3092\u8868\u3057\u307e\u3059\u3002\u4f8b\u3048\u3070\u88681\u306e\u521d\u56de\u63a5\u7a2e\u76f4\u5f8c\u306e\u6708\u7d4c\u5468\u671f\u306e\u9045\u308c\u300c1.12[0.95, 1.29]\u300d\u306f\u4eca\u56de\u3068\u540c\u3058\u7814\u7a76\u3092\u7e70\u308a\u8fd4\u3057\u884c\u3063\u305f\u5834\u5408\u3001\u6708\u7d4c\u5468\u671f\u306e\u9045\u308c\u306e\u7a0b\u5ea6\u304c95%\u306e\u78ba\u7387\u30670.95\u65e5\u304b\u30891.29\u65e5\u306e\u9593\u306b\u306a\u308b(\u3064\u307e\u308a95%\u306e\u78ba\u7387\u3067\u304a\u3088\u305d1\u65e5\u5206\u306e\u6708\u7d4c\u5468\u671f\u306e\u9045\u308c\u304c\u898b\u3089\u308c\u308b)\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u3010\u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9\u306e\u30dd\u30a4\u30f3\u30c8\u3011<\/strong><\/p>\n<ul>\n<li>mRNA\u306e\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u76f4\u5f8c\u306b\u3001\u5e73\u5747\u3057\u3066\u7d041\u65e5\u7a0b\u5ea6\u306e\u4e00\u6642\u7684\u306a\u6708\u7d4c\u5468\u671f\u306e\u9045\u308c\u304c\u751f\u3058\u3001\u305d\u306e\u9045\u308c\u306f\u63a5\u7a2e\u5f8c2\uff5e4\u56de\u76ee\u306e\u5468\u671f\u3067\u307b\u307c\u6b63\u5e38\u306b\u623b\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f(\u88681)\u3002<\/li>\n<li>\u521d\u56de\u63a5\u7a2e\uff081\u56de\u76ee\u30012\u56de\u76ee\u63a5\u7a2e\u306e\u3053\u3068\uff09\u3092\u5bfe\u8c61\u3068\u3057\u305f\u6b27\u7c73\u306e\u7814\u7a76<sup>\u2780,\u2781<\/sup>\u3067\u3082\u3001mRNA\u306e\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306b\u534a\u65e5\u304b\u30891\u65e5\u7a0b\u5ea6\u306e\u4e00\u6642\u7684\u306a\u6708\u7d4c\u306e\u9045\u308c\u304c\u751f\u3058\u3001\u305d\u306e\u5f8c\u6b63\u5e38\u306b\u623b\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u5148\u884c\u7814\u7a76\u6210\u679c\u3068\u6bd4\u3079\u3066\u3082\u3001mRNA\u306e\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306b\u304a\u3051\u308b\u6708\u7d4c\u5468\u671f\u306e\u9045\u308c\u306e\u7a0b\u5ea6\u306f\u65e5\u672c\u3068\u8af8\u5916\u56fd\u3067\u5909\u308f\u308a\u306f\u306a\u3044\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3059\u3002\u307e\u305f\u4ed6\u7814\u7a76\u3067\u306fmRNA\u306e\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3068\u4e0d\u598a\u306e\u95a2\u4fc2\u6027\u304c\u306a\u3044\u3053\u3068\u3082\u793a\u3055\u308c\u3066\u3044\u307e\u3059<sup>\u2782<\/sup>\u3002\u3053\u308c\u3089\u306e\u5148\u884c\u7814\u7a76\u306e\u60c5\u5831\u306f\u30a2\u30e1\u30ea\u30ab\u7523\u5a66\u4eba\u79d1\u5b66\u4f1a<sup>\u2783<\/sup>\u3084CDC(Centers for Disease Control and Prevention)<sup>\u2784<\/sup>\u3067\u3082\u5f15\u7528\u3055\u308c\u3066\u304a\u308a\u3001\u3044\u305a\u308c\u3082mRNA\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306e\u6708\u7d4c\u5468\u671f\u306e\u7570\u5e38\u306f\u4e00\u6642\u7684\u3067\u3001\u63a5\u7a2e\u5f8c\u306e\u4e0d\u598a\u3078\u306e\u5f71\u97ff\u306f\u306a\u3044\u3053\u3068\u304c\u8a00\u53ca\u3055\u308c\u3066\u304a\u308a\u307e\u3059\u3002\u4ee5\u4e0a\u3088\u308a\u6211\u3005\u3082mRNA\u306e\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u306e\u6708\u7d4c\u5468\u671f\u3078\u306e\u5f71\u97ff\u3092\u904e\u5ea6\u306b\u5fc3\u914d\u3059\u308b\u5fc5\u8981\u306f\u306a\u3044\u3068\u8003\u3048\u3066\u304a\u308a\u307e\u3059\u3002<\/li>\n<li>\u305d\u306e\u4ed6\u306e\u80cc\u666f\u56e0\u5b50\u3068\u3057\u3066\u3001\u5e74\u9f62\u304c\u9ad8\u3044\u4eba\u3001\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306e\u767a\u71b1\u304c\u9ad8\u3044\u4eba\u306b\u304a\u3044\u3066\u6708\u7d4c\u5468\u671f\u306e\u9045\u308c\u306e\u7a0b\u5ea6\u304c\u5927\u304d\u3044\u3053\u3068\u3001\u307e\u305f\u5375\u80de\u671f\uff08\u6392\u5375\u3059\u308b\u524d\uff09\u3067\u63a5\u7a2e\u3057\u305f\u5834\u5408\u3067\u306f\u6708\u7d4c\u304c\u9045\u308c\u308b\u4e00\u65b9\u3067\u3001\u9ec4\u4f53\u671f\uff08\u6392\u5375\u3057\u305f\u5f8c\uff09\u306b\u63a5\u7a2e\u3057\u305f\u5834\u5408\u306b\u306f\u6708\u7d4c\u5468\u671f\u306f\u5909\u308f\u3089\u306a\u3044\u3001\u3082\u3057\u304f\u306f\u77ed\u304f\u306a\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\uff08\u88682\uff09\u3002<\/li>\n<li>\u3069\u306e\u3088\u3046\u306a\u63a5\u7a2e\u306e\u6761\u4ef6\u304c\u6708\u7d4c\u5468\u671f\u306e\u9045\u308c\u306b\u7e4b\u304c\u308b\u306e\u304b\u3068\u3044\u3063\u305f\u60c5\u5831\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u305f\u3053\u3068\u306b\u3088\u308a\u3001\u4e0d\u598a\u6cbb\u7642\u306e\u8a08\u753b\u306a\u3069\u6708\u7d4c\u5468\u671f\u306e\u60c5\u5831\u304c\u91cd\u8981\u306a\u8a3a\u7642\u884c\u70ba\u306b\u304a\u3044\u3066\u3001\u672c\u7814\u7a76\u6210\u679c\u304c\u53c2\u8003\u3068\u306a\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/li>\n<li>\u300e\u30eb\u30ca\u30eb\u30ca\u300f\u30a2\u30d7\u30ea\u3001\u300e\u30eb\u30ca\u30eb\u30ca \u4f53\u6e29\u30ce\u30fc\u30c8\u300f\u4e0a\u306b\u8a18\u9332\u3055\u308c\u305f\u6708\u7d4c\u5468\u671f\u306b\u95a2\u3059\u308b\u30d3\u30c3\u30b0\u30c7\u30fc\u30bf\u306f\u75ab\u5b66\u7684\u8abf\u67fb\u306e\u7814\u7a76\u57fa\u76e4\u3068\u3057\u3066\u3001\u4eca\u5f8c\u65b0\u305f\u306b\u958b\u767a\u3055\u308c\u3046\u308b\u65b0\u898f\u306e\u6cbb\u7642\u85ac\u3084\u30ef\u30af\u30c1\u30f3\u306a\u3069\u3068\u5973\u6027\u306e\u30d8\u30eb\u30b9\u30b1\u30a2\u3078\u306e\u5f71\u97ff\u3068\u306e\u95a2\u9023\u6027\u306e\u8abf\u67fb\u3078\u5fdc\u7528\u3055\u308c\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/li>\n<li>\u6708\u7d4c\u5468\u671f\u306f\u3001\u30b9\u30c8\u30ec\u30b9\u3084\u74b0\u5883\u306e\u5909\u5316\u306a\u3069\u69d8\u3005\u306a\u8981\u56e0\u3067\u4e71\u308c\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305fmRNA\u4ee5\u5916\u306e\u30ef\u30af\u30c1\u30f3(\u30a6\u30a4\u30eb\u30b9\u30d9\u30af\u30bf\u30fc\u3084\u7d44\u63db\u3048\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u7528\u3044\u305f\u3082\u306e\u7b49) \u3084\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u4ee5\u5916\u306e\u30ef\u30af\u30c1\u30f3\u3067\u3082\u540c\u69d8\u306b\u6708\u7d4c\u5468\u671f\u306e\u9045\u308c\u304c\u751f\u3058\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059<sup>\u2781,\u2465<\/sup>\u3002\u672c\u7814\u7a76\u306f\u3001mRNA\u306e\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306e\u6708\u7d4c\u5468\u671f\u306e\u9045\u308c\u3068\u306e\u75ab\u5b66\u7684\u306a\u95a2\u9023\u3092\u660e\u3089\u304b\u306b\u3057\u305f\u3082\u306e\u3067\u3042\u308a\u3001mRNA\u30ef\u30af\u30c1\u30f3\u305d\u306e\u3082\u306e\u306e\u751f\u6b96\u6a5f\u80fd\u3078\u306e\u5f71\u97ff\u3092\u793a\u3057\u305f\u7814\u7a76\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/li>\n<\/ul>\n<p><strong><a href=\"https:\/\/www.mti.co.jp\/wp-content\/uploads\/2023\/12\/02a26045f6d6ef88e94b9f8505014734.png\" rel=\"lightbox[34316]\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter  wp-image-34322\" src=\"https:\/\/www.mti.co.jp\/wp-content\/uploads\/2023\/12\/02a26045f6d6ef88e94b9f8505014734.png\" alt=\"\" width=\"708\" height=\"460\" \/><\/a>\u3010\u80cc\u666f\u30fb\u76ee\u7684\u3011<br \/>\n<\/strong>\u3053\u308c\u307e\u3067\u8af8\u5916\u56fd\u3067\u306f\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u306b\u3001\u6708\u7d4c\u5468\u671f\u306b\u9045\u308c\u304c\u751f\u3058\u308b\u53ef\u80fd\u6027\u304c\u61f8\u5ff5\u3055\u308c\u3066\u304a\u308a\u3001\u5b9f\u969b\u306bmRNA\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u306e\u521d\u56de\u63a5\u7a2e\uff081\u56de\u76ee\u30012\u56de\u76ee\u63a5\u7a2e\u306e\u3053\u3068\uff09\u76f4\u5f8c\u306b\u534a\u65e5\u304b\u30891\u65e5\u672a\u6e80\u306e\u308f\u305a\u304b\u306a\u6708\u7d4c\u5468\u671f\u306e\u9045\u308c\u304c\u8d77\u3053\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u3001\u65e5\u672c\u4eba\u306b\u304a\u3051\u308b\u521d\u56de\u63a5\u7a2e\u5f8c\uff081\u56de\u76ee\u30012\u56de\u76ee\u63a5\u7a2e\u306e\u3053\u3068\uff09\u306e\u6708\u7d4c\u5468\u671f\u306e\u9045\u308c\u306e\u7a0b\u5ea6\u3084\u30013\u56de\u76ee\u306e\u8ffd\u52a0\u63a5\u7a2e\u306b\u3088\u308b\u5f71\u97ff\u306b\u3064\u3044\u3066\u306f\u5341\u5206\u306b\u5206\u304b\u3063\u3066\u3044\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u305d\u306e\u305f\u3081\u3001\u65e5\u672c\u4eba\u306b\u304a\u3051\u308bmRNA\u306e\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u521d\u56de\u63a5\u7a2e\u30fb\u8ffd\u52a0\u63a5\u7a2e\u5f8c\u306e\u6708\u7d4c\u5468\u671f\u306e\u9045\u308c\u306b\u95a2\u3057\u3066\u8abf\u67fb\u3092\u884c\u3044\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3068\u6708\u7d4c\u5468\u671f\u306e\u4e71\u308c\u306b\u95a2\u3059\u308b\u6b63\u3057\u3044\u75ab\u5b66\u7684\u60c5\u5831\u3092\u793e\u4f1a\u306b\u63d0\u4f9b\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u3066\u672c\u7814\u7a76\u3092\u5b9f\u65bd\u3057\u307e\u3057\u305f\u3002<\/p>\n<p><strong>\u3010\u7814\u7a76\u6982\u8981\u3011<br \/>\n<\/strong>\u7814\u7a76\u5bfe\u8c61\uff1a\u672c\u7814\u7a76\u3078\u306e\u53c2\u52a0\u306b\u3064\u3044\u3066\u540c\u610f\u3057\u3066\u3044\u308b\u300e\u30eb\u30ca\u30eb\u30ca\u300f\u30a2\u30d7\u30ea\u53ca\u3073\u300e\u30eb\u30ca\u30eb\u30ca \u4f53\u6e29\u30ce\u30fc\u30c8\u300f\u306e\u30e6\u30fc\u30b6\u30fc<br \/>\n\u7814\u7a76\u5bfe\u8c61\u671f\u9593\uff1a\u24602022\u5e747\u670812\u65e5\uff5e8\u670812\u65e5\u3001\u24612022\u5e7410\u67081\u65e5\uff5e10\u670831\u65e5<br \/>\n\u7814\u7a76\u65b9\u6cd5\uff1a\u2460\u300e\u30eb\u30ca\u30eb\u30ca\u300f\u30a2\u30d7\u30ea\u3001\u300e\u30eb\u30ca\u30eb\u30ca \u4f53\u6e29\u30ce\u30fc\u30c8\u300f\u306b\u767b\u9332\u3055\u308c\u3066\u3044\u308b\u6708\u7d4c\u5468\u671f\u306a\u3069\u306e\u30c7\u30fc\u30bf\u89e3\u6790<br \/>\n\u3000\u3000\u3000\u3000\u3000\u2461\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3084\u305d\u306e\u526f\u53cd\u5fdc\u306a\u3069\u306b\u95a2\u3059\u308b\u30a2\u30f3\u30b1\u30fc\u30c8\u8abf\u67fb<\/p>\n<p><strong>\u00a0<\/strong><\/p>\n<p><strong>\u3010\u56fd\u7acb\u6210\u80b2\u533b\u7642\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u3000\u7d30\u8c37<\/strong> <strong>\u8061\u53f2\u304b\u3089\u306e\u30b3\u30e1\u30f3\u30c8<\/strong><strong>\u3011<br 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\/>\n<\/strong>\u30bf\u30a4\u30c8\u30eb\uff1aProlongation of the Menstrual Cycle After Receipt of the Primary Series and Booster Doses of mRNA Coronavirus Disease 2019 (COVID-19) Vaccination<br \/>\n\u57f7\u7b46\u8005\uff1aSatoshi Hosoya<sup>1,2<\/sup>, Aurelie Piedvache<sup>3<\/sup>, Akari Nakamura<sup>4<\/sup>, Risa Nasu<sup>4<\/sup>, Maaya Hine<sup>4<\/sup>, Shiori Itoi<sup>3,5<\/sup>, Ryo Yokomizo<sup>1,2<\/sup>, Akihiro Umezawa<sup>1<\/sup>, Osamu Hiraike<sup>5<\/sup>, Kaori Koga<sup>5,6<\/sup>, Yutaka Osuga<sup>5<\/sup>, Satoshi Narumi<sup>7<\/sup>, and Naho Morisaki<sup>3<br \/>\n<\/sup>\u6240\u5c5e\uff1a<br \/>\n\u30001\uff09\u56fd\u7acb\u6210\u80b2\u533b\u7642\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u7814\u7a76\u6240 \u518d\u751f\u533b\u7642\u30bb\u30f3\u30bf\u30fc<br \/>\n\u30002\uff09\u6771\u4eac\u6148\u6075\u4f1a\u533b\u79d1\u5927\u5b66 \u7523\u5a66\u4eba\u79d1\u5b66\u8b1b\u5ea7<br \/>\n\u30003\uff09\u56fd\u7acb\u6210\u80b2\u533b\u7642\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u7814\u7a76\u6240 \u793e\u4f1a\u533b\u5b66\u7814\u7a76\u90e8<br \/>\n\u30004\uff09\u682a\u5f0f\u4f1a\u793e\u30a8\u30e0\u30c6\u30a3\u30fc\u30a2\u30a4 \u30d8\u30eb\u30b9\u30b1\u30a2\u4e8b\u696d\u672c\u90e8 \u30eb\u30ca\u30eb\u30ca\u4e8b\u696d\u90e8<br \/>\n\u30005\uff09\u6771\u4eac\u5927\u5b66 \u7523\u5a66\u4eba\u79d1<br \/>\n\u30006\uff09\u5343\u8449\u5927\u5b66\u5927\u5b66\u9662 \u751f\u6b96\u533b\u5b66\u8b1b\u5ea7<br \/>\n\u30007\uff09\u56fd\u7acb\u6210\u80b2\u533b\u7642\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u7814\u7a76\u6240 \u5206\u5b50\u5185\u5206\u6ccc\u7814\u7a76\u90e8<br \/>\n\u63b2\u8f09\u8a8c\uff1aObstetrics &amp; Gynecology<br \/>\nDOI\uff1a10.1097\/AOG.0000000000005476<\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u3010\u7279\u8a18\u4e8b\u9805\u3011<br \/>\n<\/strong>\u672c\u7814\u7a76\u306f\u3001\u65e5\u672c\u533b\u7642\u7814\u7a76\u958b\u767a\u6a5f\u69cb\uff08AMED\uff09\u304b\u3089\u3001\u300c\u4e8b\u696d\u540d\uff1a\u5973\u6027\u306e\u5065\u5eb7\u306e\u5305\u62ec\u7684\u652f\u63f4\u5b9f\u7528\u5316\u7814\u7a76\u4e8b\u696d\uff08AMED-WISE\uff09\u300d\u300c\u8ab2\u984c\u540d\uff1a\u30d7\u30ec\u30b3\u30f3\u30bb\u30d7\u30b7\u30e7\u30f3\u671f\u306e\u5065\u5eb7\u7ba1\u7406\u6700\u9069\u5316\u5b9f\u73fe\u306e\u305f\u3081\u306e\u30ea\u30a2\u30eb\u30ef\u30fc\u30eb\u30c9\u30c7\u30fc\u30bf\u7b49\u5927\u898f\u6a21\u30c7\u30fc\u30bf\u3092\u6d3b\u7528\u3057\u305f\u30a8\u30d3\u30c7\u30f3\u30b9\u5275\u51fa\u300d\u306b\u304a\u3044\u3066\u3001\u306e\u7814\u7a76\u8cbb\u306e\u652f\u63f4\u3092\u53d7\u3051\u3066\u5b9f\u65bd\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u3010\u51fa\u5c55\u3011<br \/>\n\u2780\uff1aEdelman A, et al. Association between menstrual cycle length and coronavirus disease 2019 (COVID-19) vaccination: AU.S. Obstet Gynecol 2022;139:481-9.<br \/>\n\u2781\uff1aGibson EA, et al. Covid-19 vaccination and menstrual cycle length in the Apple Women\u2019s Health Study. NPJ Digit Med 2022;5:165.<br \/>\n\u2782: Wesselink AK, et al. A Prospective Cohort Study of COVID-19 Vaccination, SARS-CoV-2 Infection, and Fertility. Am J Epidemiol. 2022 23;191:1383-1395.<br \/>\n\u2783\uff1aThe American College of Obstetrics and Gynecology. URL\uff1a<a href=\"https:\/\/www.acog.org\/clinical\/clinical-guidance\/practice-advisory\/articles\/2020\/12\/covid-19-vaccination-considerations-for-obstetric-gynecologic-care\">https:\/\/www.acog.org\/clinical\/clinical-guidance\/practice-advisory\/articles\/2020\/12\/covid-19-vaccination-considerations-for-obstetric-gynecologic-care<\/a> Accessed at Nov 13th, 2023.<br \/>\n\u2784\uff1aCenters for Disease Control and Prevention. URL: <a href=\"https:\/\/www.cdc.gov\/coronavirus\/2019-ncov\/vaccines\/planning-for-pregnancy.html\">https:\/\/www.cdc.gov\/coronavirus\/2019-ncov\/vaccines\/planning-for-pregnancy.html<\/a>\u00a0<br \/>\nAccessed at Nov 13th, 2023.<br \/>\n\u2465\uff1aSuzuki S, et al. No association between HPV vaccine and reported post-vaccination symptoms in Japanese young women: results of the Nagoya study. Papillomavirus Res 2018;5:96-103. doi: 10.1016\/j.pvr.2018.02.002<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u5831\u9053\u95a2\u4fc2\u306e\u65b9\u304b\u3089\u306e\u304a\u554f\u3044\u5408\u308f\u305b\u5148<br \/>\n<\/strong>\u56fd\u7acb\u6210\u80b2\u533b\u7642\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u3000\u4f01\u753b\u6226\u7565\u5c40\u00a0\u5e83\u5831\u4f01\u753b\u5ba4 \u6751\u4e0a\u30fb\u795e\u7530\u3000<br \/>\n\u96fb\u8a71\uff1a03-3416-0181\uff08\u4ee3\u8868\uff09\u3000E-mail:\u00a0<a class=\"blue\" href=\"mailto:koho@ncchd.go.jp\">koho@ncchd.go.jp\u00a0<\/a><\/p>\n<p>\n\u682a\u5f0f\u4f1a\u793e\u30a8\u30e0\u30c6\u30a3\u30fc\u30a2\u30a4 \u5e83\u5831\u5ba4<br \/>\nTEL\uff1a 03-5333-6755\u3000\u3000FAX\uff1a 03-3320-0189<br \/>\nE-mail\uff1a\u00a0<a class=\"blue\" href=\"mailto:mtipr@mti.co.jp\">mtipr@mti.co.jp<\/a>\u3000\u3000URL\uff1a\u00a0<a class=\"blue\" href=\"https:\/\/www.mti.co.jp\/\">https:\/\/www.mti.co.jp\/<\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" 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